The Graduation of Jake Moon by Barbara Park

Life hasn't been the same for Jake Moon since his grandfather, Skelly, got Alzheimer's disease. At first Jake thought, no big deal, it was just a disease that made old people forget where they put their car keys. But he was wrong. It is a big deal. A very big deal.
For one thing, he can't invite friends over because Skelly might do something embarrassing like tell them to zipper their "briskets," or Jake might reach into the freezer for a can of frozen orange juice and find Skelly's frozen pajamas there instead. He used to love spending time with his grandfather...but now he is mostly stuck fastening the Velcro on Skelly's sneakers, or wiping rice off his chin. It's like all of a sudden he's the grown-up, and Skelly's the kid. How can the one person Jake could always count on be fading as fast as — well, as the moon.